Host-microbiome co-evolution: multi-species genomics for health and disease
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Hologenomics studies the host genome plus its microbial metagenome as a single evolutionary unit (holobiont). Humans harbor 10x more microbial cells than human cells. Microbiome affects immunity, metabolism, behavior, and drug response. Hologenomic approaches enable precision microbiome medicine.
Machine learning algorithms for automated pattern recognition and biomarker discovery
Multi-omics integration for comprehensive biological understanding
Validated biomarkers and therapeutic targets for precision medicine applications