🏆 2024 Nobel Prize in Physiology or Medicine
Victor Ambros & Gary Ruvkun - Discovery of microRNA and post-transcriptional gene regulation
miR-21 (Oncogenic)
UAGCUUAUCAGACUGAUGUUGA
Upregulated in most cancers, promotes proliferation
miR-155 (Immune)
UUAAUGCUAAUCGUGAUAGGGGU
Key regulator of immune response and inflammation
let-7a (Tumor Suppressor)
UGAGGUAGUAGGUUGUAUAGUU
Downregulated in cancer, suppresses oncogenes
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